| Rank | Jugador | Equipo | Asist. |
|---|---|---|---|
| 1 | Luciano Acosta | D.C. United | 15 |
| 2 | Julian Gressel | Atlanta United | 13 |
| 3 | Nicolás Lodeiro | Seattle Sounders | 12 |
| 4 | Borek Dockal | Philadelphia Union | 12 |
| 5 | Darwin Quintero | Minnesota United | 12 |
| 6 | Diego Váleri | Portland Timbers | 12 |
| 7 | Kaku | New York RB | 11 |
| 8 | Ignacio Piatti | CF Montréal | 11 |
| 9 | Maxi Moralez | New York City | 11 |
| 10 | Almiron | Atlanta United | 11 |
| 11 | Vela | Los Angeles | 11 |
| 12 | Joao Plata | Real Salt Lake | 10 |
| 13 | Ashley Cole | Los Angeles Galaxy | 9 |
| 14 | Jefferson Savarino | Real Salt Lake | 9 |
| 15 | Romell Quioto | Houston Dynamo | 9 |
| 16 | Alberth Elis | Houston Dynamo | 9 |
| 17 | Yordy Reyna | Vancouver Whitecaps | 9 |
| 18 | Alphonso Davies | Vancouver Whitecaps | 9 |
| 19 | Romain Alessandrini | Los Angeles Galaxy | 8 |
| 20 | Diego Fagúndez | New England | 8 |
| 21 | Sebastián Blanco | Portland Timbers | 8 |
| 22 | Alejandro Silva | CF Montréal | 8 |
| 23 | Dániel Sallói | Sporting KC | 7 |
| 24 | Johnny Russell | Sporting KC | 7 |
| 25 | Cristian Penilla | New England | 7 |
| 26 | Federico Higuaín | Columbus SC | 7 |
| 27 | Maximiliano Urruti | Dallas | 7 |
| 28 | Tomás Martínez | Houston Dynamo | 7 |
| 29 | Bradley Wright-Phillips | New York RB | 7 |
| 30 | Sebastian Giovinco | Toronto | 7 |
| 31 | Cristian Roldán | Seattle Sounders | 7 |
| 32 | Y. Yotún | Orlando City | 7 |
| 33 | Miguel Ibarra | Minnesota United | 7 |
| 34 | Ibrahimovic | Los Angeles Galaxy | 6 |
| 35 | Chris Pontius | Los Angeles Galaxy | 6 |
| 36 | Róger Espinoza | Sporting KC | 6 |
| 37 | Rooney | D.C. United | 6 |
| 38 | Paul Arriola | D.C. United | 6 |
| 39 | Zoltán Stieber | D.C. United | 6 |
| 40 | Boniek García | Houston Dynamo | 6 |
| 41 | Jonathan Osorio | Toronto | 6 |
| 42 | Anton Tinnerholm | New York City | 6 |
| 43 | Josef Martínez | Atlanta United | 6 |
| 44 | Héctor Villalba | Atlanta United | 6 |
| 45 | Latif Blessing | Los Angeles | 6 |
| 46 | Diego Rossi | Los Angeles | 6 |
| 47 | Emmanuel Boateng | Los Angeles Galaxy | 5 |
| 48 | Bastian Schweinsteiger | Chicago Fire | 5 |
| 49 | Khiry Shelton | Sporting KC | 5 |
| 50 | Diego Rubio | Sporting KC | 5 |
| 51 | Chris Wondolowski | SJ Earthquakes | 5 |
| 52 | Yamil Asad | D.C. United | 5 |
| 53 | Edgar Castillo | Colorado Rapids | 5 |
| 54 | Santiago Mosquera | Dallas | 5 |
| 55 | Roland Lamah | Dallas | 5 |
| 56 | Michael Barrios | Dallas | 5 |
| 57 | Mauro Díaz | Dallas | 5 |
| 58 | Brooks Lennon | Real Salt Lake | 5 |
| 59 | Corey Baird | Real Salt Lake | 5 |
| 60 | Damir Kreilach | Real Salt Lake | 5 |
| 61 | Albert Rusnák | Real Salt Lake | 5 |
| 62 | Alex Muyl | New York RB | 5 |
| 63 | Will Bruin | Seattle Sounders | 5 |
| 64 | Sacha Kljestan | Orlando City | 5 |
| 65 | Alejandro Bedoya | Philadelphia Union | 5 |
| 66 | Kei Kamara | Vancouver Whitecaps | 5 |
| 67 | Taïder | CF Montréal | 5 |
| 68 | David Villa | New York City | 5 |
| 69 | J. dos Santos | Los Angeles Galaxy | 4 |
| 70 | Brandt Bronico | Chicago Fire | 4 |
| 71 | Graham Zusi | Sporting KC | 4 |
| 72 | Felipe Gutiérrez | Sporting KC | 4 |
| 73 | Gerso | Sporting KC | 4 |
| 74 | Valeri Qazaishvili | SJ Earthquakes | 4 |
| 75 | Florian Jungwirth | SJ Earthquakes | 4 |
| 76 | Pedro Santos | Columbus SC | 4 |
| 77 | Harrison Afful | Columbus SC | 4 |
| 78 | Milton Valenzuela | Columbus SC | 4 |
| 79 | Adams | New York RB | 4 |
| 80 | Sean Davis | New York RB | 4 |
| 81 | Florian Valot | New York RB | 4 |
| 82 | Van der Wiel | Toronto | 4 |
| 83 | Víctor Vázquez | Toronto | 4 |
| 84 | Kelvin Leerdam | Seattle Sounders | 4 |
| 85 | Chris Mueller | Orlando City | 4 |
| 86 | Haris Medunjanin | Philadelphia Union | 4 |
| 87 | Fafà Picault | Philadelphia Union | 4 |
| 88 | Jesús Medina | New York City | 4 |
| 89 | Lee Nguyen | Los Angeles | 4 |
| 90 | M. Ureña | Los Angeles | 4 |
| 91 | Adama Diomande | Los Angeles | 4 |
| 92 | Rolf Feltscher | Los Angeles Galaxy | 3 |
| 93 | B. Vincent | Chicago Fire | 3 |
| 94 | Kevin Ellis | Chicago Fire | 3 |
| 95 | Djordje Mihailovic | Chicago Fire | 3 |
| 96 | Katai | Chicago Fire | 3 |
| 97 | Yohan Croizet | Sporting KC | 3 |
| 98 | Krisztián Németh | Sporting KC | 3 |
| 99 | Ilie Sánchez | Sporting KC | 3 |
| 100 | Magnus Eriksson | SJ Earthquakes | 3 |
